خَبُثَ: كَانَ شِرّيراً أو مَاكِراً to be or become malicious, malevolent, vicious, wicked, evil-minded, bad, evil; to be or become sly, foxy, wily

خَبُثَ: كَانَ مُؤْذِياً أو كَرِيهاً to be or become noxious, harmful, pernicious, injurious; to be or become offensive, repugnant, obnoxious, abhorrent

خَبُثَ المَرَضُ أو الوَرَمُ إلخ to be or become malignant, virulent